The 5th Principle of Novice Kyusho Jitsu is Attack with Tempo or Rhythm. The purpose of this principle is to take advantage of the time it takes for the brain to react to external stimulus. It takes 1/20 or 1/5 of a second for the information from the nerve to go to the brain and then return. This time does vary depending on body health and hydration. This principle also ties in with the 3rd principle of Yin - Yang.